A study on drug resistance and disinfection -resistant gene qac(A/B)in Staphylococcus aureus / 预防医学

ABSTRACT

Objective To study the drug resistance and disinfection -resistant gene in Staphylococcus aureus isolates. Methods The sensitivity to 17 antibacterial agents was detected in 36 strains of Staphylococcus aureus by E -test.The disinfection -resistant genes qac (A /B ) were detected by PCR.Results The resistance rates of clindamycin, ciprofloxacin,erythromycin,levofloxacin,oxacillin and penicillin G were 94.44%,75.00%,94.44%,72.22%, 97.22% and 100.00%,respectively.There were no significantly difference of drug resistance rates between isolates from ICU setting and non -ICU setting (P >0.05 ),and 14 (38.89%)isolates were qac (A /B)positive.Conclusion Clinically isolated staphylococcus aureus is multi -drug -resistant and the qac (A /B)positive rate is high.