Determination and analysis of allergen specific IgE in 1 028 children with allergic dermatosis / 中国医师杂志

ABSTRACT

Objective@#To observe the differences in specific IgE of allergic diseases.@*Methods@#The allergens in 1 028 patients (including 606 cases of eczema/specific dermatitis, 319 Cases of urticaria, 103 cases of papular urticaria and prurigo) were detected by German Allergy Screen Immune mark method.@*Results@#There were statistically significant differences (P<0.05) in the positive rate of allergens among the four allergic diseases, including Penicillium notatum/ Piptocephalis/ aspergillus fumigatus/aspergillus niger/Alternaria (χ2=6.663), milk (χ2=10.320) and cashew nut (χ2=14.325); The common allergen in <1-year-old group was cat dander (22.75%), egg white (35.93%); The common allergen in 1 to 3 years old group was dog dander (22.17%), milk (61.82%) and crab (3.45%). The common allergen in>3-year-old group was dust mite (10.77%), cockroach (3.52%), Penicillium notatum/Piptocephalis/ aspergillus fumigatus/aspergillus niger/Alternaria (21.32%), Short ragweed/artemisia/Humulus scandens/quinoa (14.73%). The positive rate of specific IgE against house dust in the third quarter was the highest (17.78%) and the difference was statistically significant (χ2=14.443, P=0.002). Among the statistically significant difference in the positive rate of specific IgE between eczema/atopic dermatitis in different age groups (χ2=10.204, P=0.006), the positive rate in the group of 1 to 3 years was the highest.@*Conclusions@#Different diseases, ages, and seasonal specific allergens are different, individualized treatment can be carried out according to disease types, ages and seasons.