Your browser doesn't support javascript.
loading
Progress of phosphatidylinositol 3-kinase signaling pathway and its inhibitors in lymphoma / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma ; (12): 568-571, 2019.
Artigo em Chinês | WPRIM | ID: wpr-798249
ABSTRACT
The over-activation of phosphatidylinositol 3-kinase (PI3K) signaling pathway is closely related to the occurrence and development of malignant tumors. The abnormal expression of this pathway is involved in the regulation of cell growth, malignant transformation, apoptosis and metastasis. The targeted therapy for specific sites of PI3K signaling pathway is a new research hotspot. A variety of different types of PI3K inhibitors have been marketed or entered clinical trials and have shown considerable efficacy in the treatment of malignant lymphomas. In this view, the recent advances in activation patterns of PI3K signaling pathway in lymphoma and PI3K inhibitors are summarized.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Journal of Leukemia & Lymphoma Ano de publicação: 2019 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Journal of Leukemia & Lymphoma Ano de publicação: 2019 Tipo de documento: Artigo