Assessment of bi-ventricular remodeling in patients with hypertrophic cardiomyopathy after modified Morrow surgery by three-dimensional speckle tracking echocardiography / 中华超声影像学杂志

ABSTRACT

Objective@#To assess the bi-ventricular remodeling in patients with hypertrophic obstructive cardiomyopathy (HOCM) after modified Morrow surgery by three-dimensional speckle tracking echocardiography (3D-STE).@*Methods@#Twenty-eight patients with HOCM who underwent modified Morrow surgery from August 2013 to September 2016 in Xijing Hospital were consecutively included in this study. Routine and full-volume echocardiographic images were collected before and after surgery, 3D-STE echocardiographic data were analyzed by TomTec software to calculate left and right ventricular end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) and ejection fraction (EF), as well as the longitudinal strain(LS), circumferential strain(CS), radial strain(RS) of the 16 segments of left ventricle. The left atrial maximum volume(LAVmax), left atrial minimum volume (LAVmin), left atrial stroke volume(LASV), left atrial ejection fraction(LAEF) were obtained, as well as right ventricular longitudinal strain of septum [RVLS(S)], right ventricular longitudinal strain of free wall[RVLS(FW)], tricuspid annular planesystolic excursion(TAPSE), right ventricular fractional area change(RVFAC).@*Results@#Compared with baseline, the IVS thickness were significantly reduced, LVOT pressure gradient were significantly decreased, LVOT diameter were increased significantly (all P<0.05). The LS in the basal part of anterior and lateral wall were increased significantly (all P<0.05). The CS in basal and middle part of lateral wall were increased significantly (all P<0.05). The RS in basal part of anterior, lateral and posterior wall, as well as in the middle part of anterior and lateral wall were increased significantly( all P<0.05). The LAVmax, LAVmin and LASV were decreased, and the LAEF was increased(all P<0.05). The RVLS(FW) and the TAPSE were increased significantly( all P<0.05).@*Conclusions@#After modified Morrow surgery in HOCM patients, the morphological remodeling of left ventricle, left atrium and right ventricle are improved, accompanied by the improvement of the function. 3D-STE is valuable in evaluating the efficacy of modified Morrow surgery in HOCM patients.