Advances in research on the pathogenesis of pathogen infection promoting Alzheimer′s disease / 中华神经科杂志

ABSTRACT

The research on the pathogenesis of Alzheimer′s disease (AD) is constantly updated nowadays. The amyloid cascade hypothesis and the theory of tau protein are the mainstream theory of the pathogenesis of AD. The theory that pathogen infection, including intestinal flora, increases the incidence of AD has gradually gained attention and fully supplements existing doctrines. By reviewing the literature on the pathogenesis of AD in the past 10 years, the possible mechanisms by which pathogens increase the incidence of AD were summarized and early interventions were proposed.