Correlation analysis of mandibular condyle volume and external ear volume in M2a type of hemifacial microsomia / 中华整形外科杂志

ABSTRACT

Objective@#To investigate the correlation between mandibular condyle volume and external ear volume in M2a type of hemifacial microsomia.@*Methods@#19 patients with M2a type of hemifacial microsomia diagnosed by CT scan in the Shanghai Ninth People′s Hospital from August 2017 to December 2018 were included, and the head CT data were obtained. At the same time, 19 healthy people were recruited as volunteers and obtain CT data of their heads as control. The Mimics 15.0 software was used for 3D reconstruction of CT data, measure the volume of mandibular condyle and external ear. SPSS 25.0 software was used to analyze the correlation between mandibular volume and external ear volume, as well as the difference between bilateral mandibular condyle volume (healthy side mandibular condyle volume-affected side mandibular condyle volume) and bilateral external ear volume difference (healthy side external ear volume-affected side external ear volume), and the correlation was obtained by spearman correlation coefficient analysis. P<0.05 indicates that the difference was statistically significant.@*Results@#The data of 19 cases of M2a type of hemifacial microsomia and 19 healthy volunteers were analyzed. The left and right volume of bilateral mandibular condyle in healthy volunteers was (1 309.23±420.63) mm3, (1 325.93±425.60) mm3(P=0.904), the left and right volume of external ear was (7 854.18±2 005.77) mm3, (7 862.63±1 994.02) mm3(P=0.990), bilateral development was synchronous, there was no statistical difference. There was a significant positive correlation between mandibular condyle volume and external ear volume in healthy volunteers (P=0.004, rs=0.772). The volume of healthy and affected mandibular condyle in the patients with M2a type of hemifacial microsomia was (1 160.89±549.07) mm3, (509.55±303.88) mm3 (P=0.006), and the volume of healthy and affected external ear was (7 418.19±2 434.93) mm3and (2 029.99±1 080.37) mm3 (P=0.007). The development is not synchronized in the mandibular condyle and external ear in M2a type of hemifacial microsomia, but the mandibular condyle volume is significantly positively correlated with the external ear volume(healthy side P=0.008, rs=0.740; affected side P=0.004, rs=0.709), and the affected part of the mandibular condyle and the external ear development (the volume difference between the mandibular condyle or the external ear volume) also has the same performance(P=0.006, rs=0.753).@*Conclusions@#There is a significant positive correlation between mandibular condyle volume and external ear volume in patients with M2a type of hemifacial microsomia.