Timing and selection of antiviral therapy with nucleos(t)ide analogues for prevention of hepatitis B virus-related HCC / 中华肝脏病杂志
Chinese Journal of Hepatology
; (12): 827-830, 2019.
Article
em Zh
| WPRIM
| ID: wpr-801302
Biblioteca responsável:
WPRO
ABSTRACT
Hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma (HCC) in China. The occurrence of HCC can significantly be reduced with effective long-term antiviral treatment. Since the widespread clinical use of nucleos(t)ide analogues, such as entecavir and tenofovir that has a strong potency and high genetic barrier to resistance; the detection rate of HBV DNA in serum of patients with chronic hepatitis B is no more than 85% ~ 95%, but HCC can still occur in a small number of patients. This article will review whether the timing and selection of NAs treatment differ to prevent and reduce the incidence of HCC.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Hepatology
Ano de publicação:
2019
Tipo de documento:
Article