The role of primary cilium in bone tissue mechanotransduction / 医用生物力学
Journal of Medical Biomechanics
; (6): E580-E583, 2013.
Article
em Zh
| WPRIM
| ID: wpr-804236
Biblioteca responsável:
WPRO
ABSTRACT
Bone tissues constantly receive the mechanical stimulation and maintain the dynamic balance of bone formation and resorption. Currently, the mechanism of how bone tissues sense the mechanical stimulation is still unknown. An increasing number of studies have shown that primary cilium may be the mechanical sensor of bone tissues. The primary cilium maybe transfer the extracellular mechanical signals into intracellular biochemical message through them, and the mechanical stimulation received by bone tissues can regulate bone remodeling finally. This article reviews the current researches on primary cilium, predicts the research tendency and tries to lay some foundation for the use of primary cilium to prevent and treat osteoporosis.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Medical Biomechanics
Ano de publicação:
2013
Tipo de documento:
Article