Advances in the revascularization of prefabricated flap / 中华整形外科杂志

ABSTRACT

The principle of prefabricated flap is to establish a new blood supply system, in order to supply the free flap or random flap. The key to produce a prefabricated flap is the establishment of blood supply. Currently, a series of methods could be used to promote vascular regeneration and flap survival, including chemical stimulation, stem cell transplantation, hyperbaric oxygen therapy, biomaterials application, nerve implantation, tissue expansion and microsurgical technique. The reasonable combination of multiple methods could better promote the angiogenesis of the prefabricated flap, and ultimately realize the survival of the flap, thus create a new way for the repairment of complex tissue defects.