Clinical significance of quantitative level of hepatitis B core antibody / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 948-952, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-809693
ABSTRACT
Hepatitis B core antibody (anti-HBc) targets viral core protein and is produced in patients with hepatitis B virus (HBV) infection, and seroconversion occurs in the early stage of infection and often lasts for a lifetime. Qualitative detection of anti-HBc has been used in clinical practice for many years, while the clinical significance of its quantitative level remains unclear. A novel anti-HBc immunoassay based on double-antigen sandwich ELISA has been developed in recent years and lays a foundation for illustrating the change in the quantitative level of anti-HBc (qAnti-HBc) in HBV infection and its clinical significance. Several recent studies have revealed that qAnti-HBc is associated with the degree of hepatitis activity and response to pharmacotherapy and may become an important basis for selecting antiviral drugs, optimizing therapeutic regimen, and predicting treatment outcome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
/
Pesquisa qualitativa
Idioma:
Chinês
Revista:
Chinese Journal of Hepatology
Ano de publicação:
2017
Tipo de documento:
Artigo
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