Prevalence and possible causes of hypouricemia at a tertiary care hospital
The Korean Journal of Internal Medicine
;
: 971-976, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-81003
ABSTRACT
BACKGROUND/AIMS:
We aimed to investigate the prevalence and possible causes of hypouricemia in the Korean population and to compare our findings with published results of other populations.METHODS:
We examined the serum uric acid levels of 30,757 subjects who had their uric acid values measured at least once during a 1-year period. All individuals with hypouricemia (serum uric acid < 2.0 mg/dL, n = 424) were reviewed with respect to medical drug history and concomitant diseases previously identified as being associated with hypouricemia.RESULTS:
The prevalence of hypouricemia was 4.14% (299/7,223) among inpatients and 0.53% (125/23,534) among outpatients, for an overall prevalence of 1.39% (424/30,757). Possible causes associated with hypouricemia were found to be solid or hematologic malignancies (n = 86), diabetes mellitus (n = 56), and therapeutic drugs (n = 29). The medications were allopurinol (n = 11), angiotensin II receptor blockers (n = 10), salicylates (n = 6), febuxostat (n = 1), and warfarin (n = 1). In the remaining 226 individuals, the cause of hypouricemia was not identified.CONCLUSIONS:
Hypouricemia is relatively common in the Korean population compared to those of other countries. The possible causes associated with hypouricemia are related to underlying diseases and medications.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pacientes Ambulatoriais
/
Ácido Úrico
/
Varfarina
/
Atenção Terciária à Saúde
/
Salicilatos
/
Alopurinol
/
Prevalência
/
Neoplasias Hematológicas
/
Diabetes Mellitus
/
Antagonistas de Receptores de Angiotensina
Tipo de estudo:
Estudo de etiologia
/
Estudo de prevalência
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
The Korean Journal of Internal Medicine
Ano de publicação:
2016
Tipo de documento:
Artigo
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