Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea
Journal of the Korean Association of Oral and Maxillofacial Surgeons
;
: 49-57, 2020.
Artigo
em Inglês
| WPRIM
| ID: wpr-811269
ABSTRACT
OBJECTIVES:
This study aimed to understand the nationwide patterns of antibiotic prescription after tooth extraction in adult patients.MATERIALS ANDMETHODS:
This study analyzed dental records from the National Health Insurance Service–National Sample Cohort (NHIS–NSC) database on 503,725 tooth extractions performed in adults (≥19 years) during 2011–2015. Patient sex, age, household income, systemic disease (diabetes mellitus and hypertension), type of dental institution, region of dental institution, year of prescription, and type of tooth extraction procedure were considered. The antibiotic prescription rate and broad-spectrum antibiotic prescription frequency were analyzed using chi-squared tests. Factors affecting the prescription of broad-spectrum antibiotics were evaluated using multivariate logistic regression analysis.RESULTS:
The rate of antibiotic prescription after tooth extraction was 81.85%. Penicillin was most commonly prescribed (45.25%), followed by penicillin with beta-lactamase inhibitors (18.76%), metronidazole (12.29%), and second- to fourth-generation cephalosporins (11.52%). The proportion of broad-spectrum antibiotics used among all prescribed antibiotics was 45.88%.CONCLUSION:
The findings of this study demonstrate that the rate of antibiotic prescription after tooth extraction is higher in Korea than in other countries. Furthermore, broad-spectrum antibiotics are used more frequently, which may indicate unnecessary drug prescription, an important contributor to antibiotic resistance.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Penicilinas
/
Prescrições de Medicamentos
/
Dente
/
Extração Dentária
/
Resistência Microbiana a Medicamentos
/
Modelos Logísticos
/
Cefalosporinas
/
Registros Odontológicos
/
Características da Família
/
Estudos de Coortes
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Journal of the Korean Association of Oral and Maxillofacial Surgeons
Ano de publicação:
2020
Tipo de documento:
Artigo
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