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Prescreening skin test effectiveness in predicting hypersensitivity to iodinated contrast media
Journal of the Korean Medical Association ; : 155-158, 2020.
Artigo em Coreano | WPRIM | ID: wpr-811298
ABSTRACT
Hypersensitivity reaction to iodinated contrast media (ICM) is a persistent clinical issue owing to widespread use of computed tomography (CT) examinations. The question of whether routine performance of skin tests can predict hypersensitivity reactions to contrast media remains unresolved. Recently, a prospective study was performed to evaluate the role of an intradermal skin test as a prescreening test for hypersensitivity reactions to ICM. Fifteen (0.5%) of the 2,843 patients had positive skin test results prior to scheduled CT scans. However, none of the patients experienced a hypersensitivity reaction after administration of full-dose ICM. Meanwhile, 19 patients who experienced hypersensitivity reactions to an ICM challenge showed negative skin test results. The sensitivity and positive predictive value of skin tests for hypersensitivity reaction to ICM were both 0%. More studies should be conducted to confirm the uselessness of prescreening skin tests. In conclusion, a prescreening intradermal skin test prior to a CT scan has no significant clinical value as a tool for predicting hypersensitivity reactions to ICM. Therefore, prescreening skin tests should not be routinely performed.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pele / Testes Cutâneos / Tomografia Computadorizada por Raios X / Valor Preditivo dos Testes / Estudos Prospectivos / Meios de Contraste / Hipersensibilidade Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos Idioma: Coreano Revista: Journal of the Korean Medical Association Ano de publicação: 2020 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pele / Testes Cutâneos / Tomografia Computadorizada por Raios X / Valor Preditivo dos Testes / Estudos Prospectivos / Meios de Contraste / Hipersensibilidade Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Humanos Idioma: Coreano Revista: Journal of the Korean Medical Association Ano de publicação: 2020 Tipo de documento: Artigo