Megastigmane glucosides isolated from Dichrocephala benthamii / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 288-291, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-812113
ABSTRACT
The present study was designed to investigate the chemical constituents of the whole herb of Dichrocephala benthamii. A new megastigmane glucoside (compound 1), together with its four known analogues (compounds 2-5), was obtained. Their structures were elucidated on the basis of spectroscopic analyses (UV, IR, MS, and 1D and 2D NMR). The absolute configuration of compound 1 was assigned on the basis of CD method and chemical evidence. In addition, their cytotoxicity against human hepatoma cells (HepG-2) was evaluated by the MTT method. Compound 5 showed weak activity against HepG-2, while the other compounds did not show remarkable inhibitory effects.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Ensaios de Seleção de Medicamentos Antitumorais
/
Medicamentos de Ervas Chinesas
/
Estrutura Molecular
/
Química
/
China
/
Asteraceae
/
Cicloexanonas
/
Norisoprenoides
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2017
Tipo de documento:
Artigo
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