A new Lycopodium alkaloid from Phlegmariurus fargesii / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 373-376, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-812273
ABSTRACT
AIM@#To investigate the chemical constituents from the whole plants of Phlegmariurus fargesii.@*METHOD@#Compounds were isolated by repeated silica gel column chromatography. Their structures were elucidated by spectroscopic methods and chemical correlation. The acetylcholinesterase (AChE) inhibitory activity of the isolated compounds was evaluated.@*RESULTS@#A new Lycopodium alkaloid, lycopodine N-oxide (1), along with lycopodine (2), 8,15-dehydrolycopodine (3), 6α-hydroxylycopodine (4), deacetyllycoclavine (5), N-methylhuperzine B (6), lycodine (7), and phlegmarine (8), was isolated.@*CONCLUSION@#Compound 1 is a new Lycopodium alkaloid, and compound 3 was obtained from nature for the first time. Other alkaloids are isolated from this plant for the first time.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Quinolizinas
/
Extratos Vegetais
/
Estrutura Molecular
/
Química
/
Huperzia
/
Alcaloides
Idioma:
Inglês
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2014
Tipo de documento:
Artigo
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