New limonoids isolated from the bark of Melia toosendan / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 946-950, 2018.
Article
em En
| WPRIM
| ID: wpr-812335
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WPRO
ABSTRACT
Two new limonoids, 12-ethoxynimbolinins G and H (compounds 1 and 2), and one known compound, toosendanin (Chuanliansu) (compound 3), were isolated from the bark of Melia toosendan. Their structures were elucidated by spectroscopic analysis and X-ray techniques. The absolute configuration of toosendanin (3) was established by single-crystal X-ray diffraction. Compounds 1-3 were evaluated for their cytotoxicity against five tumor cell lines.
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Assunto principal:
Farmacologia
/
Difração de Raios X
/
Extratos Vegetais
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Estrutura Molecular
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Química
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Casca de Planta
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Melia
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Limoninas
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Linhagem Celular Tumoral
/
Proliferação de Células
Limite:
Humans
Idioma:
En
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2018
Tipo de documento:
Article