Identfication of new naphthalenones from Juglans mandshurica and evalution of their anticancer activities / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 707-710, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-812491
ABSTRACT
Two new naphthalenone compounds were isolated from green walnut husks of Juglans mandshurica and their structures were identified as 4-butoxybutoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one (1), 4-ethoxyethoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one (2). Compounds 1 and 2 were named as Juglanstetralone A (1) and Juglanstetralone B (2). Compound 1 showed more significant anti-tumor activity than 2 against gastric cancer BGC-823 cells, wih the IC50 of 125.89 (g(mL(-1).
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Neoplasias Gástricas
/
Extratos Vegetais
/
Carcinoma
/
Química
/
Juglans
/
Linhagem Celular Tumoral
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Fitoterapia
Limite:
Humanos
Idioma:
Inglês
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2015
Tipo de documento:
Artigo
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