A new phenylpropanoid glycoside from the fruits of Illicium simonsii / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 20-23, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-812719
ABSTRACT
AIM@#To study the constituents and bioactivity of Illicium simonsii.@*METHODS@#The extracts of the fruits of Illicium simonsii were submitted to a combination of chromatographic materials, silica gel, ODS column chromatography and finally preparative HPLC to obtain eight compounds which were further evaluated for their cytotoxicity by MTT method.@*RESULTS@#A new phenylpropanoid glycolside, 2, 4-dihydroxy-allylbenzene-2-O-β-D-glucopyranoside (1), together with seven characteristic sesquiterpene lactones, oligandrumin B (2), oligandrumin D (3), anisatin (4), veranisatin D (5), pseudomajucin (6), 1α-hydroxy-3-deoxy-pseudoanisatin (7), 8α-hydroxy-10-deoxycyclomerrillianolide (8) were isolated.@*CONCLUSION@#Compound 1 is new. Compounds 1, 2, 3, 5-8 were isolated from this plant for the first time. None of the isolates showed inhibitory effects on the growth of non-small cell lung tumor cell line A549.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sesquiterpenos
/
Extratos Vegetais
/
Química
/
Carcinoma Pulmonar de Células não Pequenas
/
Illicium
/
Tratamento Farmacológico
/
Frutas
/
Lactonas
/
Monossacarídeos
Limite:
Humanos
Idioma:
Inglês
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2012
Tipo de documento:
Artigo
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