Current status for animal models of intensive care unit acquired muscle weakness / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 691-696, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-813209
ABSTRACT
Intensive care unit acquired muscle weakness (ICU-AW) is a neuromuscular complication secondary to severe illness. The essence for this disease is skeletal muscle dysfunction. With the development of medical technology, the survival rate for severe patients has been significantly improved. The long term complications for the severe patients with ICU-AW are getting more and more common, and they seriously affect the quality of life and prognosis of patients. However, the current treatment is ineffective. Establishment of ICU-AW animal model is an important way to study the pathogenesis and intervention targets for this disease. There are many risk factors for this disease, and the principles for ICU-AW animal models are not the same at home and abroad, and the methods of preparation are different. The choice of a reasonable animal model is important for the reliability of the results.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Qualidade de Vida
/
Taxa de Sobrevida
/
Reprodutibilidade dos Testes
/
Mortalidade
/
Estado Terminal
/
Músculo Esquelético
/
Debilidade Muscular
/
Modelos Animais de Doenças
/
Unidades de Terapia Intensiva
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2018
Tipo de documento:
Artigo
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