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Magnetic resonance imaging features of glioma with Brg/Brm associated factor 53a expression / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences) ; (12): 485-490, 2019.
Artigo em Chinês | WPRIM | ID: wpr-813276
ABSTRACT
To explore the magnetic resonance imaging (MRI) characteristics of glioma with Brg/Brm-associated factor 53a (BAF53a) expression.


Methods:

A total of 121 patients with glioma was divided into a BAF53a high expression group (n=79) and a low expression group (n=42) according to the results of immunohistochemistry. Then the MRI characteristics, including lesion location, number, boundary, maximum diameter, peripheral edema, midline structure shift, homogeneity, cystic necrosis, hemorrhage, strengthening degree, ependymal strengthening, pia mater enhancement, deep white matter invasion and lesion across the midline (total 14 items), were analyzed.


Results:

The results showed that there were significance difference in lesion border, lesion edema, enhancement of the lesion, and deep white matter invasion between the 2 groups (all P<0.05).


Conclusion:

The MRI characteristics, such as lesion border, lesion edema degree, enhancement degree of the lesion and deep white matter invasion, might be associated with BAF53a expression in gliomas.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Neoplasias Encefálicas / Imageamento por Ressonância Magnética / Proteínas Cromossômicas não Histona / Actinas / Proteínas de Ligação a DNA / Glioma / Metabolismo / Necrose Limite: Humanos Idioma: Chinês Revista: Journal of Central South University(Medical Sciences) Ano de publicação: 2019 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Neoplasias Encefálicas / Imageamento por Ressonância Magnética / Proteínas Cromossômicas não Histona / Actinas / Proteínas de Ligação a DNA / Glioma / Metabolismo / Necrose Limite: Humanos Idioma: Chinês Revista: Journal of Central South University(Medical Sciences) Ano de publicação: 2019 Tipo de documento: Artigo