Biotoxicology and biodynamics of silica nanoparticle / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 6-8, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-813778
ABSTRACT
OBJECTIVE@#To investigate the toxicology and biodynamics of silica nanoparticle.@*METHODS@#The silica nanoparticles were injected into mice through tail vein, and the mice were amphimixised, the urine was collected in different time, variations of pathology in organs and tissues of the mice were detected. At the same time, the silica nanoparticles' distribution in the tissues was observed through electron microscope.@*RESULTS@#The silica nanoparticles were detected in all tissues and urine of the mice. The injected mice can reproduce as normal.@*CONCLUSION@#The silica nanoparticles do not have toxicity and can be used in vivo.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Teste de Materiais
/
Farmacocinética
/
Distribuição Tecidual
/
Transfecção
/
Dióxido de Silício
/
Nanoestruturas
/
Toxicidade
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2006
Tipo de documento:
Artigo
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