Establishment of Experimental Murine Peritonitis Model with Hog Gastric Mucin for Carbapenem-Resistant Gram-Negative Bacteria / 감염과화학요법
Infection and Chemotherapy
;
: 57-61, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-81402
ABSTRACT
Animal models are essential to studies of infectious diseases. The use of mice to test bacterial infection has been extensively reported. However, methods applied to clinical isolates, particularly for carbapenem-resistant bacteria, must be tailored according to the infection models and bacteria used. In this study, we infected 6-week-old female BALB/c mice intraperitoneally with different strains of resistant bacteria plus 3% hog gastric mucin. This method was found to be efficient and readily applicable for investigation of carbapenem-resisant Gram-negative pathogens (e.g., Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii) detected in Korea.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peritonite
/
Pseudomonas aeruginosa
/
Bactérias
/
Infecções Bacterianas
/
Acinetobacter
/
Doenças Transmissíveis
/
Modelos Animais
/
Escherichia coli
/
Mucinas Gástricas
/
Bactérias Gram-Negativas
Limite:
Animais
/
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Infection and Chemotherapy
Ano de publicação:
2017
Tipo de documento:
Artigo
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