Effect of antipsychotic drugs on life quality of schizophrenic patients: one year follow-up study / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 850-855, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-814209
ABSTRACT
OBJECTIVE@#To compare the effect of 7 antipsychotic drugs on the life quality of schizophrenia patients including chlorpromazine, sulpiride, clozapine, risperidone, olanzapine, quetiapine, and aripiprazole.@*METHODS@#A total of 1,227 stable schizophrenic patients within 5 years onset who took 1 of the 7 study medications as maintenance treatment were followed up for 1 year at 10 China sites. Patients were evaluated by the short form-36 health survey (SF-36) at the baseline and at the end of 1 year.@*RESULTS@#The life quality was improved obviously at the end of the follow-up. There was significant difference in body pain, vitality, and mental health (P<0.05) among these antipsychotic drugs.@*CONCLUSION@#All 7 antipsychotic drugs can improve the life quality of schizophrenia patients. Atypical antipsychotic drugs, especially olazapine and quetiapine, are superior to typical antipsychotic drugs in improving life quality.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Qualidade de Vida
/
Esquizofrenia
/
Antipsicóticos
/
Benzodiazepinas
/
Inquéritos e Questionários
/
Seguimentos
/
Usos Terapêuticos
/
Dibenzotiazepinas
/
Tratamento Farmacológico
/
Fumarato de Quetiapina
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2009
Tipo de documento:
Artigo
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