Ultrasonic elastography and molybdenum X-ray photography in differential diagnosis of breast diseases / 中南大学学报(医学版)

ABSTRACT

OBJECTIVE@#To compare the accuracy of ultrasonic elastography(UE) with molybdenum X-ray photography(MX-rP) in their ability to differentiate benign and malignant breast lesions.@*METHODS@#Eighty-three females with 101 lesions in the breast were prospectively studied. Pathologic outcome was used as the golden diagnosis criterion. The sensitivity, specificity, accuracy, Youden index, positive and negative predictive values of UE for diagnosing breast diseases were compared. Receiver operating characteristic (ROC) curve was used to assess the diagnostic value of UE.@*RESULTS@#Sensitivity of UE was 87.06%, specificities, accuracy, and Youden index were 93.05%, 91.08%, and 83.30%, respectively. The positive and negative predictive values were 94.36% and 80.10%. Those of MX-rP were 72.40%, 83.33%, 80.19%, 87.74%, 89.55%, and 63.52%, respectively. The positive and negative-likelihood ratio for UE was 12.41(95%CI, 5.90 to 26.88) and 0.14(95%CI, 0.06 to 0.30); and those for MX-rP, the values were 4.34(95%CI, 1.63 to 11.42) and 0.33(95%CI, 0.19 to 0.63), respectively. Area under ROC in ultrasonic elastography was 0.954(95%CI, 0.912 to 0.996).@*CONCLUSION@#UE has better diagnostic value than MX-rP in breast masses.