Immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice / 中南大学学报(医学版)

ABSTRACT

OBJECTIVE@#To explore the immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice.@*METHODS@#The immunosuppressive mouse model was established by using hydrocortisone. Huangqi Fuzhengtang and Yupingfeng San apozema were given to the mice intragastrically. The contents of hemolysin, IL-2, and INF-gamma in the mouse serum and the expression of CD3(+), CD4(+), and CD8(+) in the peripheral blood lymphocytes were measured.@*RESULTS@#Huangqi Fuzhengtang could obviously elevate the contents of hemolysin, IL-2, INF-gamma and the ratio of CD4(+) and CD8+, which was more effective than Yupingfeng San.@*CONCLUSION@#Huangqi Fuzhengtang could improve the immune function in the immunosuppressive mice.