Research progress in aldose reductase / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 395-400, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-814433
ABSTRACT
Aldose reductase is a member of aldehyde-keto reductase superfamily widely existing in the kidney, adrenal gland, lens, retina, nerve, heart, placenta, brain, skeletal muscle, testis, blood vessels, lung, liver, et al. It is a reduced nicotinamide-adenine dinucleotide phosphate (NADPH)-dependent enzyme catalyzing the reduction of various aldehydes and ketones to the corresponding alcohol. It is involved in many oxidative stress diseases, cell signal transduction and cell proliferation process as well as diabetes complications. In recent years, some progress has been made in research of the activity and gene regulation of aldose reductase and the relation with many common diseases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Rodanina
/
Transdução de Sinais
/
Aldeído Redutase
/
Estresse Oxidativo
/
Usos Terapêuticos
/
Complicações do Diabetes
/
Proliferação de Células
/
Tratamento Farmacológico
/
Inibidores Enzimáticos
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2010
Tipo de documento:
Artigo
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