Efficacy of sequential therapy with pantoprazole in gastro esophageal reflux disease / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 799-802, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-814504
ABSTRACT
OBJECTIVE@#To observe the clinical efficacy of sequential therapy with pantoprazole in patients with gastro esophageal reflux disease (GERD).@*METHODS@#A total of 80 patients with GERD were double-blindedly randomized into 2 groups 40 patients received sequential therapy with pantoprazole 40 mg injection, twice daily for 2 weeks, and then pantoprazole 40 mg oral administration,twice daily for 2 weeks; the other 40 patients received pantoprazole 40 mg oral administration alone,twice daily for 4 weeks. Doctors and patients recorded the severity and frequency of heartburn before and during the treatment. The curative effects of the 2 groups were compared.@*RESULTS@#The total effective rate in the sequential therapy group was higher than that of the oral administration group(95.0% vs 77.5%, P<0.05).@*CONCLUSION@#Pantoprazole sequential therapy is effective for GERD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esquema de Medicação
/
Refluxo Gastroesofágico
/
Método Duplo-Cego
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
2-Piridinilmetilsulfinilbenzimidazóis
/
Inibidores da Bomba de Prótons
/
Pantoprazol
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2011
Tipo de documento:
Artigo
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