Pharmacological intervention of conditioned fear and its extinction / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 968-972, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-814757
ABSTRACT
Conditioned fear and its abnormal extinction are involved in the psychopathology of anxiety disorders, such as posttraumatic stress disorder (PTSD). Cognitive enhancing agents have been demonstrated to alter fear extinction in many animal research literatures. The present review has examined the pharmacological role of gamma-aminobutyric acid (GABA), glutamatergic, cholinergic, adrenergic, dopaminergic, and cannabinoid as well as compounds able to alter the epigenetic and neurotrophic mechanism in fear extinction, highlighting great hope for the future treatment of anxiety disorders with new agents based on the fear extinction.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transtornos de Ansiedade
/
Farmacologia
/
Psicologia
/
Transtornos de Estresse Pós-Traumáticos
/
Canabinoides
/
Nootrópicos
/
Condicionamento Psicológico
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Extinção Psicológica
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2012
Tipo de documento:
Artigo
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