MicroRNA in the regulation of nervous system development / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 323-328, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-814881
ABSTRACT
Several types of molecules, including the small non-coding RNAs, are involved in the precision regulation of neural development. The expression of microRNAs appears in a specific spatialtemporal sequence during the neural development, and abnormal expression may lead to neural dysplasia. MicroRNAs also play important roles in the regulation of cell biological behaviors in terms of survival, proliferation and differentiation. Neural stem cells are the mother cell of the nervous system. The proliferation, differentiation and migration of neural stem cells are tightly controlled so as to generate appropriate number and phenotype of daughter cells to ensure normal neural development. MicroRNAs are involved in the regulation of neural stem cell proliferation and differentiation via affecting the expression and function of their target mRNAs.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Diferenciação Celular
/
Biologia Celular
/
MicroRNAs
/
Proliferação de Células
/
Células-Tronco Neurais
/
Sistema Nervoso
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2013
Tipo de documento:
Artigo
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