Progress in study on effect of harmine on bone and cartilage metabolism / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 328-332, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-815034
ABSTRACT
Harmine, a β-carboline alkaloid, is widely distributed in the plants, animals as well as in human tissues and body fluids. Harmine has various types of pharmacological activities including antimicrobial, antiplasmodial, antioxidative, antitumor, antimutagenic, antidiabetic, vasorelaxant and central excitation properties. Moreover, it can exert regenerative and protective effects on bone and cartilage tissues by regulating the proliferation, differentiation and metabolism of osteoclasts, osteoblasts and chondrocytes. These features make harmine a novel candidate for the prevention and treatment of bone and cartilage diseases, such as osteoporosis, bone fracture and osteoarthritis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteoartrite
/
Osteoblastos
/
Osso e Ossos
/
Cartilagem
/
Diferenciação Celular
/
Condrócitos
/
Harmina
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2016
Tipo de documento:
Artigo
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