Toll-like receptors and non-resolving inflammation-related cancer / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 202-207, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-815193
ABSTRACT
Toll-like receptors (TLRs) is a type of pattern recognition receptors (PRRs), which are singular, non-catalytic and highly homologous. TLRs not only play significant roles in natural immunity, but also act as a bridge between innate immunity and adaptive immunity. Recent studies have revealed that TLRs play critical roles in the development of non-resolving inflammation-related cancer,including the formation of tumor microenvironment, invasion and metastasis, immune escape, etc. Further investigation into the mechanisms responsible for the function of TLRs will be of great value in tumor prevention, early diagnosis and therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Receptores Toll-Like
/
Microambiente Tumoral
/
Inflamação
/
Invasividade Neoplásica
/
Metástase Neoplásica
/
Neoplasias
Tipo de estudo:
Estudo de rastreamento
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2015
Tipo de documento:
Artigo
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