Nucleic acid aptamers in diagnosis of diseases / 中南大学学报(医学版)

ABSTRACT

Aptamers are single-stranded oligonucleotide ligands selected from a random pool of oligonucleotide sequences by systematic evolution of ligands by exponential enrichment. With the advantages of binding to targets with high specificity and affinity, aptamers have been used in the diagnosis widely, such as biochemistry detection, discovery of new tumor markers, molecular imaging, pathogenic and microorganism detection, showing a good application prospect.