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Is Endoscopic Resection for Type 1 Gastric Neuroendocrine Tumors Essential for Treatment?: Multicenter, Retrospective Long-term Follow-up Results
The Korean Journal of Helicobacter and Upper Gastrointestinal Research ; : 13-18, 2016.
Artigo em Inglês | WPRIM | ID: wpr-81705
ABSTRACT
BACKGROUND/

AIMS:

Treatment of gastric neuroendocrine tumors is determined by type and size of the lesion. This study aimed to compare the long-term efficacy of observation and endoscopic resection for type 1 gastric neuroendocrine tumors without metastasis. MATERIALS AND

METHODS:

Among the 223 cases of gastric neuroendocrine tumors diagnosed between January 1996 and December 2011, 104 cases were type 1 gastric neuroendocrine tumors. Sixty-seven patients were treated endoscopically and 27 patients were observed without treatment. Endoscopic mucosal resection, endoscopic submucosal dissection, and polypectomy were the methods used for endoscopic treatment. Therapeutic efficacy and rates of complication and recurrence were evaluated retrospectively.

RESULTS:

In the endoscopic resection group, complete resection was observed in 53 patients (79.1%), and recurrence was observed in 14 patients (20.9%). On analysis of the observation group, no change was observed in 19 patients (70.4%), and tumor progression was observed in 8 patients (29.6%). Median follow-up duration was 49 months (31~210 months). No mortality was reported in either group during follow-up.

CONCLUSIONS:

Observation of type 1 gastric neuroendocrine tumors without metastasis yields results similar to those produced by endoscopic resection. Observation alone may be a safe treatment.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Estômago / Estudos Retrospectivos / Seguimentos / Mortalidade / Tumores Neuroendócrinos / Endoscopia / Metástase Neoplásica Tipo de estudo: Estudo observacional / Estudo prognóstico Limite: Humanos Idioma: Inglês Revista: The Korean Journal of Helicobacter and Upper Gastrointestinal Research Ano de publicação: 2016 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Recidiva / Estômago / Estudos Retrospectivos / Seguimentos / Mortalidade / Tumores Neuroendócrinos / Endoscopia / Metástase Neoplásica Tipo de estudo: Estudo observacional / Estudo prognóstico Limite: Humanos Idioma: Inglês Revista: The Korean Journal of Helicobacter and Upper Gastrointestinal Research Ano de publicação: 2016 Tipo de documento: Artigo