Your browser doesn't support javascript.
loading
A Case of Epstein-Barr-Virus-Associated Lymphocytic Interstitial Pneumonia / 소아알레르기및호흡기학회지
Pediatric Allergy and Respiratory Disease ; : 307-313, 2009.
Artigo em Coreano | WPRIM | ID: wpr-81759
ABSTRACT
Lymphocytic interstitial pneumonia (LIP) is a benign lymphoproliferative disorder characterized histologically by diffuse infiltration with predominantly mature lymphocytes, plasma cells and reticuloendothelial cells in the alveolar septae and along the lymphatic vessels. LIP is an uncommon disease frequently associated with autoimmune diseases such as Sj?gren's syndrome, systemic lupus erythematosus, chronic active hepatitis, thyroiditis, myasthenia gravis, autoimmune hemolytic anemia and Human Immunodeficiency Virus (HIV) or Epstein- Barr virus (EBV) infection. LIP can progress to pulmonary or systemic lymphoma. LIP in children has variable disease courses such as spontaneous resolution, episodic worsening or progression to frank respiratory failure. Intravenous immunoglobulin and corticosteroids yield variable results, and some children may respond to them for several years. We report herein a case of EBV-associated, HIV-negative LIP diagnosed by thoracoscopic lung biopsy and a clonality study in a 5 year-old boy who was admitted with recurrent coughing and dyspnea. The patient was treated and fully recovered with methylprednisolone and high dose acyclovir. At the 3-year follow-up, he showed no clinical symptom despite increased EBV copy in bronchoalveolar lavage and progressive bronchiectasis in the right middle lobe.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Plasmócitos / Insuficiência Respiratória / Doenças Autoimunes / Glândula Tireoide / Tireoidite / Vírus / Biópsia / Bronquiectasia / Aciclovir / Imunoglobulinas Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Criança / Humanos Idioma: Coreano Revista: Pediatric Allergy and Respiratory Disease Ano de publicação: 2009 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Plasmócitos / Insuficiência Respiratória / Doenças Autoimunes / Glândula Tireoide / Tireoidite / Vírus / Biópsia / Bronquiectasia / Aciclovir / Imunoglobulinas Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Criança / Humanos Idioma: Coreano Revista: Pediatric Allergy and Respiratory Disease Ano de publicação: 2009 Tipo de documento: Artigo