Analysis of the Success Rate and Reliability of Fibroscan in Screening Fatty Liver / 中山大学学报(医学科学版)

ABSTRACT

@#【Objective】Fibroscan has been recommended by multiple clinical guidelines as the first choice among the non-invasive tools for evaluating hepatic steatosis and liver stiffness. The study herein assessed the factors related to the success rate and reliability of the measurement.【Methods】A total of 788 volunteers from Year 2018′ s staff physical checkup in The First Affiliated Hospital of Sun Yat- sen University were recruited. Relationship between age ，gender， body mass index ，waist circumference of the subjects ，and the operator′s experience ，and their effect on success rate and reliability were analyzed.【Results】had a higher detection rate for fatty liver as compared with ultrasound（55.9% vs.39.9% ，P<0.001）. Detection failure and unreliable measurements occurred in only 1.4% of all the participants. Success rate was not associated with gender ，but decreased significantly with increased age ，body mass index and waist circumference （P<0.05）. LSM IQR/Median increased accordingly ，thus reduced the reliability of the measurement. With accumulated number of measurements by the same operator，so did the success rate and reliability of the results. An operator with more than 300 measurements could be deemed as experienced operator.【Conclusions】The success rate and reliability of the measurement was affected by increased age ，body mass index ，waist circumference and operator′ s experience. Fixed operator could also achieve very high success rate and reliable measurement using Fibroscan after short- term training.