Research progress on Wnt3 gene polymorphism and susceptibility to non-syndromic cleft lip and palate / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 1217-1221, 2019.
Artigo
em Chinês
| WPRIM
| ID: wpr-818171
ABSTRACT
Non-syndromic cleft lip with/without cleft palate (NSCL/P) is a common congenital disease worldwide, and its etiology is related to the combination of genetic and environmental factors. Although genome-wide association analysis did not involve Single Nucleotide Polymorphisms (SNPs) in Wnt genes, it has been reported that SNPs in Wnt genes are related to NSCL/P, and the study of SNPs of Wnt genes and its corresponding phenotypic effect is helpful to explain the etiological mechanism of NSCL/P. In recent years, Wnt3 gene related to NSCL/P, rs142167, rs3809857, rs9890413 and other teratopoietic single nucleotide loci are the main teratopoietic single nucleotide loci studied most, and the research conclusions on the correlation between Wnt3 gene polymorphism and NSCL/P are obviously different in different populations. This paper reviews the research progress on the correlation between Wnt3 gene polymorphism and NSCL/P.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Medical Postgraduates
Ano de publicação:
2019
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS