An HIV1/2 point of care test on sputum for screening TB/HIV co-infection in Central India - Will it work?
Asian Pacific Journal of Tropical Medicine
;
(12): 216-219, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-820539
ABSTRACT
OBJECTIVE@#To determine whether the OraQuick® HIV-1/2 Assay (OraSure Technologies, Inc., Bethlehem, PA, USA) in sputum is a valid tool for HIV surveillance among TB patients.@*METHODS@#A cross sectional study was carried out on sputa of patients diagnosed with tuberculosis. Sputa were tested for antibodies to HIV using OraQuick® HIV-1/2 Assay (OraSure Technologies, Inc., Bethlehem, PA, USA). The results were compared with results of serum ELISA.@*RESULTS@#Compared to serum ELISA, the OraQuick® HIV-1/2 Assay in sputum specimens reported 90% sensitivity (9/10) and 100% specificity (307/307), with a positive predictive value of 100% (95%CI 66.37%-100.00%) and a negative predictive value of 99.68% (95%CI 98.20%-99.99%).@*CONCLUSIONS@#This testing method may provide a useful strategy for conducting HIV surveillance in possible co-infected TB patients at peripheral centres. Since there is no investment on infrastructure, it may be possible for paramedical health professionals to carry out the test, particularly in areas with low HIV endemicity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Escarro
/
Tuberculose Pulmonar
/
Sangue
/
Ensaio de Imunoadsorção Enzimática
/
Infecções por HIV
/
Química
/
Programas de Rastreamento
/
Estudos Transversais
/
Sensibilidade e Especificidade
/
HIV-1
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Adolescente
/
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Asian Pacific Journal of Tropical Medicine
Ano de publicação:
2013
Tipo de documento:
Artigo
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