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Progress of astrocytes and their exosomes in central nervous system disease / 国际儿科学杂志
International Journal of Pediatrics ; (6): 915-918, 2019.
Artigo em Chinês | WPRIM | ID: wpr-823469
ABSTRACT
Astrocytes exist in the central nervous system widely,through cell-cell communication in neurovascular units,playing an important role in providing metabolic support for neurons,regulating nerve function and plasticity and so on.There is evidence that exosomes play a key regulatory role in intercellular communication by carrying natural cargo molecules and participate in a variety of pathophysiological processes.However,the role of astrocyte-derived exosome in central nervous system diseases is largely unknown.In this paper,the classification,characteristics,biomarkers,physiological functions,functions of astrocyte-derived exosome and their roles in central nervous system diseases are reviewed,for a deeper understanding of the role of astrocytes in central nervous system diseases.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: International Journal of Pediatrics Ano de publicação: 2019 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: International Journal of Pediatrics Ano de publicação: 2019 Tipo de documento: Artigo