The role of cervicography in cervical cancer screening / 대한산부인과학회잡지

ABSTRACT

OBJECIVE: Although incidence of the cervical cancer has been very high, it is possible to detect the early cervical cancer with screening methods. Among the screening methods of cervical cancer, Papanicolaou smear has lower sensitivity and higher false negative rate. The goal of this study is to evaluate the usefulness of cervicography in cervical cancer screening. METHODS: The data of Papanicolaou smear and cervigram has been obtained from 292 patients. The age range varied between 20 and 78 years with the average age of 42. Histologic specimens were obtained from patients whose abnormalities were detected by either Papanicolaou smear or cervigram. A total of 101 patients received a biopsy. We calculated sensitivity, specificity, positive predictive values, negative predictive values, false negative rates and false positive rates. RESULTS: Results for Papanicolaou smear are as follows; sensitivity, 60.8%, specificity, 93.4%, positive predictive values, 66.0%, negative predictive values, 91.8%, false negative rates, 39.2% and false positive rates, 6.6%. In cervicography, sensitivity, 70.1%, specificity, 85.5%, positive predictive values, 56.3%, negative predictive values, 94.5%, false negative rates, 23.5% and false positive rates, 11.6%. Results for the combined methods are sensitivity with 82.4%, specificity with 92.5%, positive predictive values with 51.9%, negative predictive values with 97.0%, false negative rates with 11.8% and false positive rates with 16.2%. CONCLUSION: Cervicography is an effective method to screen cervical cancer. When cervicography is used with Papanicolaou smear, the detection rate of cervical cancer will be increased.