Relationship between CYP2C19 gene polymorphism and clopidogrel resistance／ / 心血管康复医学杂志

ABSTRACT

Clopidogrel possesses different therapeutic effects due to individual patient differences .Clopidogrel resist‐ance occurs in some patients .Many researches have indicated that CYP2C19 gene polymorphism possesses close cor‐relation with variability of platelets after receiving clopidogrel .The present article made a review on related litera‐ture ,to explore the possibility that CYP2C19 gene detection guides clopidogrel antiplatelet therapy .