Value of complement system in the diagnosis of systemic lupus erythematosus / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
; (12): 1002-1006, 2019.
Article
em Zh
| WPRIM
| ID: wpr-824901
Biblioteca responsável:
WPRO
ABSTRACT
The complement system plays a major role in systemic lupus erythematosus (SLE). At present, complement component 3(C3) and component 4(C4) are the diagnostic markers in the internationally recognized standard of SLE classification. Complement C3 and C4 can play a role in the diagnosis of SLE patients, but they are not very specific diagnostic markers. Therefore, it is important to find more better biomarkers of SLE. In this review, the latest findings in complement-focused research in SLE were explored. Complement level, cell-bound complement activation products and membrane-bound complement regulatory proteins are associated with the pathogenesis of SLE. They may become SLE biomarkers and aid the diagnosis and monitoring of patients with this disease.
Texto completo:
1
Índice:
WPRIM
Tipo de estudo:
Diagnostic_studies
Idioma:
Zh
Revista:
Chinese Journal of Laboratory Medicine
Ano de publicação:
2019
Tipo de documento:
Article