Association of hypoxic microenvironment with the development and progression of liver diseases / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 1891-1895, 2020.
Artigo
em Chinês
| WPRIM
| ID: wpr-825052
ABSTRACT
Hypoxic microenvironment is a common phenomenon of liver diseases and runs through the whole process of the development and progression of liver diseases. In recent years, the research on liver fibrosis and hypoxic microenvironment of hepatocellular carcinoma has attracted more and more attention. Hypoxia-inducible factor (HIF) is the most important hypoxic stress factor found at present. This article reviews the characteristics of hypoxic microenvironment in the liver and liver diseases and further elaborates on the association of HIF overexpression with hepatocyte damage, formation of fibrosis, and malignant transformation of hepatocytes.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Clinical Hepatology
Ano de publicação:
2020
Tipo de documento:
Artigo
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