Churg-Strauss Syndrome Showing Green Colored Polycyclic Patches / 대한피부과학회지

ABSTRACT

Churg-Strauss syndrome (CSS) or allergic granulomatous angiitis is a rare systemic vasculitis with tissue and blood eosinophilia. A 37-year-old woman with a 2-year history of allergic rhinitis and asthma presented with polycyclic patches on both extremities and trunk. Laboratory studies revealed peripheral blood eosinophilia, hyper-IgE, and positivity for ANA (1:40, speckled pattern). Skin biopsy specimens showed endothelial cell swelling, perivascular and interstitial eosinophilic infiltration with nuclear dust in the dermis. She was treated with methylprednisolone and showed an improvement in symptoms. Two years later she developed a tingling sensation on her right hand and right lower extremity along with aggravation of skin lesions. The skin examination revealed erythematous papules and greenish patches on buttock and finger joints. On the histological examination of the patches on the buttock, prominent extravascular eosinophilic infiltration, endothelial cell swelling and degenerative collagen fibers were observed in the dermis.