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A Comprehensive Review of the Treatment of Atopic Eczema
Allergy, Asthma & Immunology Research ; : 181-190, 2016.
Artigo em Inglês | WPRIM | ID: wpr-83206
ABSTRACT
Atopic eczema (AE) is a chronic, inflammatory skin disorder which usually develops in early childhood. In spite of intensive investigations, the causes of AE remain unclear, but are likely to be multifactorial in nature. Environmental factors or genetic-environmental interactions seem to play a key role in disease progression. Among various measures of AE managment, cutaneous hydration, which improves barrier function and relieve itchiness, may be helpful to reduce the need for topical steroid use and therefore should be used as a basic treatment. Avoiding aggravating factors is also a basic treatment of AE. Standard medical treatment with a pharmacologic approach may be necessary if basic treatment fails to control symptoms satisfactorily. Recently, more attention is given to a proactive therapeutic by regular intermittent application of low potency steroids or topical calcineurin inhibitors to prevent new flares. Furthermore, various targeted biologics are being introduced for AE control and are proposed as promising therapies. This paper provides a summary of the recent literature on the manangement of AE and a treatment guideline.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pele / Esteroides / Produtos Biológicos / Epidemiologia / Progressão da Doença / Calcineurina / Dermatite Atópica / Eczema Tipo de estudo: Guia de Prática Clínica Idioma: Inglês Revista: Allergy, Asthma & Immunology Research Ano de publicação: 2016 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pele / Esteroides / Produtos Biológicos / Epidemiologia / Progressão da Doença / Calcineurina / Dermatite Atópica / Eczema Tipo de estudo: Guia de Prática Clínica Idioma: Inglês Revista: Allergy, Asthma & Immunology Research Ano de publicação: 2016 Tipo de documento: Artigo