Seroconversion of red blood cell antibody in ABO-incompatible living donor liver transplantation-a case report- / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 252-256, 2020.
Artigo
| WPRIM
| ID: wpr-834025
ABSTRACT
Background@#; Liver transplantation usually requires blood transfusion, and a red blood cell (RBC) antibody screen is essential for the prevention of a hemolytic reaction. Since proper ABO-compatible grafts are lacking, ABO-incompatible living donor liver transplantation (ABO-i LDLT) with desensitization is a feasible therapy. Desensitization includes intravenous rituximab injection and plasmapheresis before surgery.Case A 60-year-old female was diagnosed with hepatitis B virus-related hepatocellular carcinoma and planned for ABO-i LDLT. She tested positive in a RBC antibody screen over two years; however, she tested negative for the test after desensitization. Clinicians noted the seroconversion during induction, and thus, a delay in the preparation of adequate packed RBC was unavoidable. @*Conclusions@#Even when the latest RBC antibody screen is negative after immunosuppression, clinicians should consider the possibility of a prior positive result to promote safer medical treatment and management.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Revista:
Korean Journal of Anesthesiology
Ano de publicação:
2020
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS