Correlation between carotid viscoelasticity and hemodynamics based on ultrasound shear wave dispersion imaging / 第二军医大学学报

ABSTRACT

Objective: To measure the carotid viscoelasticity using ultrasound shear wave dispersion (USWD), and to explore the correlation between the viscoelasticity and hemodynamics. Methods: Forty-fve volunteers without history of cardiovascular and cerebrovascular events were recruited and divided into elder group (≥50 years old, n=23) and younger group (<50 years old, n = 22) according to the median age. The common carotid arteries were detected by USWD, and SWER (elastic index) and SWDR (viscous index) were obtained. Hemodynamic parameters, including velocity time integral (VTI), peak systolic velocity (PSV), end-diastolic velocity (EDV), and mean flow velocity (MFV), were measured using Doppler ultrasound. Correlations between SWER, SWDR and hemodynamic parameters were analyzed using Pearson analysis. Results: The SWER, SWDR, VTI, PSV, EDV and MFV in the elder group were significantly lower than those in the younger group (P<0.05, P<0.01). The SWER was positively correlated with VTI, PSV, EDV and MFV (r=0.354, 0.400, 0.467 and 0.310; P<0.01, P<0.05). The SWDR was negatively correlated with VTI and PSV (r= - 0.481 and - 0.522, both P<0.01), but positively correlated with MFV (r=0.352, P<0.01). Conclusion: USWD may identify the change of carotid viscoelasticity, and the change of viscoelasticity is related to hemodynamics.