Vascular pathophysiologic characteristics of different types of basilar atherosclerotic infarction / 第二军医大学学报

ABSTRACT

Objective To use high-resolution magnetic resonance imaging (HR-MRI) for studying the vascular remodeling and plaque characteristics of two types of basilar atherosclerotic infarction; branch occlusive disease (BOD) and nonBOD. Methods Thirty-two patients with symptomatic basilar artery stenosis were divided into BOD and non-BOD groups, with 18 patients in BOD group and 14 in non-BOD group. All the patients received 3. 0T HR-MRI enhancement scanning for the basilar artery wall. The wall thickness and plaque area of steno-occlusive basilar artery at the maximal stenosis were measured and analyzed, so as to assess the vascular remodeling and plaque characteristics. Results HR-MRI scanning showed that the stenosis of non-BOD group was more obvious than that of BOD group ([68. 9 ± 19. 1]% vs [43. 8 ± 18. 8]%, P = 0. 017). Compared with BOD group, positive remodeling wasmore frequently observed in non-BOD (57. 2% vs 16. 7%, P = 0. 036). The wall area index of BOD group was also significantly lower than that of non-BOD group (P<0. 001). Eccentric enhancement was the main form for the two types of basilar atherosclerotic infarction in study, and the plaque enhancements were not significantly different between BOD and non-BOD groups (P = 0. 196); however, the enhancement degree of BOD group was significantly milder than that of the non-BOD group ([39. 9 ± 23. 2]% vs [65. 3 ± 21. 1]%, P=0. 004). Conclusion BOD and non BOD have different vascular remodelings and plaque characteristics.