Comparison between LARS system and autografts in anterior cruciate ligament reconstruction: A meta analysis / 第二军医大学学报

ABSTRACT

Objective To compare the clinical efficacy and safety between LARS system and autografts in anterior cruciate ligament (ACL) reconstruction. Methods The PubMed database, China. National Knowledge Infrastructure (CNKI), Chinese biomedical literature database (CBMdisc), and Wanfang database were searched to obtain the published article comparing the LARS and autografts for ACL reconstruction. The references, of the retrieved articles were also read for related articles. Results A total of 9 articles with 456 cases were included in this study. The results showed that Lysholm and Tegner scores were improved significantly after LARS replacement (Lysholm MD=50. 05, 95% CI 48. 41-51. 68; Tegner MD = 4. 41; 95% CI 3. 40-5. 42). Compared with autografts, the improvements of Lysholm and Tegner scores for LARS replacement were more significant 2 years postoperatively (Lysholm MD=0. 20, 95% CI 0. 04-0. 35; Tegner MD=0. 18, 95% CI 0. 040. 32). Meanwhile, complication (such as synovitis) rate of LARS replacement was low2 years postoperatively, showing no notable difference with that of autograft techniques. Conclusion The LARS artificial ligament is effective and safe for ACL reconstruction. LARS has more advantages than autografts concerning the stability 2 years postoperatively. However, high] quality studies with long-term follow-up are required for further confirmation.