QRS duration in evaluating ventricular dyssynchrony in patients with chronic systolic heart failure / 第二军医大学学报

ABSTRACT

Objective: To observe the types, prevalence of cardiac dyssynchrony in patients of chronic systolic heart failure (SHF) , and to investigate the value of QRS duration >135 ms in selecting patients for cardiac resynchronization therapy (CRT). Methods: Forty-five patients with SHF were randomly divided into two groups according to QRS width Group 1 (QRS width 135 ms could finely predict the presence of interventricular dyssynchrony, with a sensitivity of 80% and a specificity of 87. 5% ; while the same cutoff value to predict intraventricular dyssynchrony only yielded a sensitivity of 44. 1 % and specificity of 73. 6%. Conclusion: Intraventricular dyssynchrony and(or) interventricular dyssynchrony has a high prevalence in patients with SHF. A QRS duration cutoff value higher 135 ms can well evaluate the cardiac mechanical dyssynchrony in clinical practice, which may be of value for optimizing selection of CRT candidates and reducing the nonresponders.