Study on chemical constituents of Duchesnea indica Andr. Focke / 第二军医大学学报

ABSTRACT

Objective: To investigate the chemical constituents in the EtOAc fraction of the EtOH extract of Duchesnea indica Andr. Focke. Methods: Extraction was done with 95% EtOH. EtOAc fraction of the EtOH extract was isolated and purified by column chromatography using silica gel,RP-C18,Sephadex LH-20 and HPLC. The structures of the compounds were identified by their physico-chemical properties and spectral analysis. Results: Thirteen compounds were obtained from the EtOAc fraction of Duchesnea indica Andr. Focke and they were identified as euscaphic acid(1),arjunic acid(2),p-hydroxy cinnamic acid (3),apigenin(4),kaempferol(5),2α-hydroxy ursolic acid(6),2α-hydroxy oleanolic acid(7),tomentic acid(8),kaii-ichigeside F1 (9), potengriffioside A (10), rosamultin (11), kaempferol-3-O-β-D-glucoside (12), and isoquercitrin (13). Conclusion: The compounds 2-5,10, and 12 have been isolated from the genus of Duchesnea for the first time.